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Location, Location, Location: Altered Transcription Factor Trafficking in Neurodegeneration
Neurons may be particularly sensitive to disruptions in transcription factor trafficking. Survival and injury signals must traverse dendrites or axons, in addition to soma, to affect nuclear transcriptional responses. Transcription factors exhibit continued nucleocytoplasmic shuttling; the predomina...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2220049/ https://ncbi.nlm.nih.gov/pubmed/17917581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/nen.0b013e318156a3d7 |
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