In vitro and in vivo characterization of A-796260: a selective cannabinoid CB(2) receptor agonist exhibiting analgesic activity in rodent pain models

BACKGROUND AND PURPOSE: Selective cannabinoid CB(2) receptor agonists have demonstrated analgesic activity across multiple preclinical pain models. AM1241 is an indole derivative that exhibits high affinity and selectivity for the CB(2) binding site and broad spectrum analgesic activity in rodent mo...

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Detalhes bibliográficos
Main Authors: Yao, B B, Hsieh, G C, Frost, J M, Fan, Y, Garrison, T R, Daza, A V, Grayson, G K, Zhu, C Z, Pai, M, Chandran, P, Salyers, A K, Wensink, E J, Honore, P, Sullivan, J P, Dart, M J, Meyer, M D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2219533/
https://ncbi.nlm.nih.gov/pubmed/17994110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707568
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