Control of separate pathogenic autoantibody responses marks MHC gene contributions to murine lupus

Previous studies have suggested that MHC and non-MHC genes contribute to the development of autoimmune disease in F(1) hybrids of New Zealand black (NZB) and white (NZW) mice. We conducted a genome-wide screen of 148 female (NZB × NZW)F(1) × NZB backcross mice to map dominant NZW genetic loci linked...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Vyse, Timothy J., Halterman, Richard K., Rozzo, Stephen J., Izui, Shozo, Kotzin, Brian L.
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1999
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22194/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10393954/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.14.8098
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