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Spleen tyrosine kinase Syk is critical for sustained leukocyte adhesion during inflammation in vivo

BACKGROUND: During inflammation, β(2)-integrins mediate leukocyte adhesion to the endothelium accompanied by the activation of the spleen tyrosine kinase Syk. RESULTS: We investigated leukocyte adhesion and rolling in cremaster muscle venules before and during stimulation with fMLP using mice with a...

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Detalhes bibliográficos
Main Authors: Frommhold, David, Mannigel, Ingrid, Schymeinsky, Jürgen, Mocsai, Attila, Poeschl, Johannes, Walzog, Barbara, Sperandio, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2217554/
https://ncbi.nlm.nih.gov/pubmed/18045459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-8-31
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