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Voltage Dependence of Slow Inactivation in Shaker Potassium Channels Results from Changes in Relative K(+) and Na(+) Permeabilities

Time constants of slow inactivation were investigated in NH(2)-terminal deleted Shaker potassium channels using macro-patch recordings from Xenopus oocytes. Slow inactivation is voltage insensitive in physiological solutions or in simple experimental solutions such as K(+) (o)//K(+) (i) or Na(+) (o)...

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Autors principals: Starkus, John G., Heinemann, Stefan H., Rayner, Martin D.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2217199/
https://ncbi.nlm.nih.gov/pubmed/10653891
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