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Probing the Cavity of the Slow Inactivated Conformation of Shaker Potassium Channels

Slow inactivation involves a local rearrangement of the outer mouth of voltage-gated potassium channels, but nothing is known regarding rearrangements in the cavity between the activation gate and the selectivity filter. We now report that the cavity undergoes a conformational change in the slow-ina...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Panyi, Gyorgy, Deutsch, Carol
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2154382/
https://ncbi.nlm.nih.gov/pubmed/17438120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200709758
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