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Proton Probing of the Charybdotoxin Binding Site of Shaker K(+) Channels

We have investigated the interaction of charybdotoxin (CTX) with Shaker K channels. We substituted a histidine residue for the wild-type phenylalanine (at position 425) in an inactivation-removed channel. The nature of the imidazole ring of the histidine provides the ability to change the charge on...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Perez-Cornejo, Patricia, Stampe, Per, Begenisich, Ted
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Rockefeller University Press 1998
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2217115/
https://ncbi.nlm.nih.gov/pubmed/9482710
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