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Rod outer segment structure influences the apparent kinetic parameters of cyclic GMP phosphodiesterase

Cyclic GMP hydrolysis by the phosphodiesterase (PDE) of retinal rod outer segments (ROS) is a key amplification step in phototransduction. Definitive estimates of the turnover number, kcat, and of the Km are crucial to quantifying the amplification contributed by the PDE. Published estimates for the...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1994
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2216889/
https://ncbi.nlm.nih.gov/pubmed/7931138
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