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Divalent cation competition with [3H]saxitoxin binding to tetrodotoxin- resistant and -sensitive sodium channels. A two-site structural model of ion/toxin interaction

Monovalent and divalent cations competitively displace tetrodotoxin and saxitoxin (STX) from their binding sites on nerve and skeletal muscle Na channels. Recent studies of cloned cardiac (toxin-resistant) and brain (toxin-sensitive) Na channels suggest important structural differences in their toxi...

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Библиографические подробности
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 1993
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2216764/
https://ncbi.nlm.nih.gov/pubmed/8384241
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