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Modeling Hox gene regulation in digits: reverse collinearity and the molecular origin of thumbness
During the development of mammalian digits, clustered Hoxd genes are expressed following a collinear regulatory strategy, leading to both the growth of digits and their morphological identities. Because gene dosage is a key parameter in this system, we used a quantitative approach, associated with a...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Cold Spring Harbor Laboratory Press
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2216694/ https://ncbi.nlm.nih.gov/pubmed/18245448 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1631708 |
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