A dermal HOX transcriptional program regulates site-specific epidermal fate

Reciprocal epithelial–mesenchymal interactions shape site-specific development of skin. Here we show that site-specific HOX expression in fibroblasts is cell-autonomous and epigenetically maintained. The distal-specific gene HOXA13 is continually required to maintain the distal-specific transcriptio...

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Autors principals: Rinn, John L., Wang, Jordon K., Allen, Nancy, Brugmann, Samantha A., Mikels, Amanda J., Liu, Helen, Ridky, Todd W., Stadler, H. Scott, Nusse, Roel, Helms, Jill A., Chang, Howard Y.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2008
Matèries:
Research Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2216690/
https://ncbi.nlm.nih.gov/pubmed/18245445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1610508
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