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Purified Wnt5a Protein Activates or Inhibits β-Catenin–TCF Signaling Depending on Receptor Context

The Wnts comprise a large class of secreted proteins that control essential developmental processes such as embryonic patterning, cell growth, migration, and differentiation. In the most well-understood “canonical” Wnt signaling pathway, Wnt binding to Frizzled receptors induces β-catenin protein st...

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Detalhes bibliográficos
Main Authors: Mikels, Amanda J, Nusse, Roel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1420652/
https://ncbi.nlm.nih.gov/pubmed/16602827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0040115
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