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Sirt1 Deficiency Attenuates Spermatogenesis and Germ Cell Function

In mammals, Sirt1, a member of the sirtuin family of proteins, functions as a nicotinamide adenine dinucleotide-dependent protein deactylase, and has important physiological roles, including the regulation of glucose metabolism, cell survival, and mitochondrial respiration. The initial investigation...

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Autors principals: Coussens, Matthew, Maresh, John G., Yanagimachi, Ryuzo, Maeda, Gregg, Allsopp, Richard
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2216432/
https://ncbi.nlm.nih.gov/pubmed/18270565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001571
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