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A covalently bound photoisomerizable agonist. Comparison with reversibly bound agonists at electrophorus electroplaques

After disulphide bonds are reduced with dithiothreitol, trans-3- (α-bromomethyl)-3’-[α- (trimethylammonium)methyl]azobenzene (trans-QBr) alkylates a sulfhydryl group on receptors. The membrane conductance induced by this “tethered agonist” shares many properties with that induced by reversible agoni...

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Hlavní autoři: Lester, HA, Krouse, ME, Nass, MM, Wassermann, NH, Erlanger, BF
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 1980
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2215740/
https://ncbi.nlm.nih.gov/pubmed/6246192
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