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A covalently bound photoisomerizable agonist. Comparison with reversibly bound agonists at electrophorus electroplaques

After disulphide bonds are reduced with dithiothreitol, trans-3- (α-bromomethyl)-3’-[α- (trimethylammonium)methyl]azobenzene (trans-QBr) alkylates a sulfhydryl group on receptors. The membrane conductance induced by this “tethered agonist” shares many properties with that induced by reversible agoni...

詳細記述

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書誌詳細
主要な著者: Lester, HA, Krouse, ME, Nass, MM, Wassermann, NH, Erlanger, BF
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 1980
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2215740/
https://ncbi.nlm.nih.gov/pubmed/6246192
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