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Role of hindbrain in inner ear morphogenesis: Analysis of Noggin knockout mice

Signaling from rhombomeres 5 and 6 of the hindbrain is thought to be important for inner ear patterning. In Noggin -/- embryos, the gross anatomy of the inner ear is distorted and malformed, with cochlear duct outgrowth and coiling most affected. We attributed these defects to a caudal shift of the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bok, Jinwoong, Brunet, Lisa J., Howard, Omar, Burton, Quianna, Wu, Doris K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2215324/
https://ncbi.nlm.nih.gov/pubmed/17900554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2007.08.013
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