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Transient retinoic acid signaling confers anterior-posterior polarity to the inner ear
Vertebrate hearing and balance are based in complex asymmetries of inner ear structure. Here, we identify retinoic acid (RA) as an extrinsic signal that acts directly on the ear rudiment to affect its compartmentalization along the anterior-posterior axis. A rostrocaudal wave of RA activity, generat...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3017143/ https://ncbi.nlm.nih.gov/pubmed/21173260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010547108 |
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