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Functional interaction between human topoisomerase IIα and retinoblastoma protein

DNA topoisomerase II—an essential nuclear enzyme in DNA replication and transcription, chromatin segregation, and cell cycle progression—is also a target of clinically useful anticancer drugs. Preliminary observations of a positive correlation between the expression of topoisomerase (topo) IIα and t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bhat, Uppoor G., Raychaudhuri, Pradip, Beck, William T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC22152/
https://ncbi.nlm.nih.gov/pubmed/10393912
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