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Local anesthetics: hydrophilic and hydrophobic pathways for the drug- receptor reaction
The properties of Na channels of the node of Ranvier are altered by neutral, amine, and quaternary local anesthetic compounds. The kinetics of the Na currents are governed by a composite of voltage- and time- dependent gating processes with voltage- and time-dependent block of channels by drug. Conv...
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| Формат: | Artigo |
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| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
1977
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2215053/ https://ncbi.nlm.nih.gov/pubmed/300786 |
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