Receptor Revision of Immunoglobulin Heavy Chain Variable Region Genes in Normal Human B Lymphocytes

Contrary to the general precepts of the clonal selection theory, several recent studies have provided evidence for the secondary rearrangement of immunoglobulin (Ig) genes in peripheral lymphoid tissues. These analyses typically used transgenic mouse models and have only detected secondary recombina...

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Autores principales: Wilson, Patrick C., Wilson, Kenneth, Liu, Yong-Jun, Banchereau, Jacques, Pascual, Virginia, Capra, J. Donald
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2000
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213516/
https://ncbi.nlm.nih.gov/pubmed/10839804
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