T Cell Receptor (Tcr)-Mediated Repertoire Selection and Loss of Tcr Vβ Diversity during the Initiation of a Cd4(+) T Cell Response in Vivo

We recently described a novel way to isolate populations of antigen-reactive CD4(+) T cells with a wide range of reactivity to a specific antigen, using immunization with a fixed dose of nominal antigen and FACS(®) sorting by CD4(high) expression. Phenotypic, FACS(®), functional, antibody inhibition...

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Bibliographic Details
Main Authors: Fassò, Marcella, Anandasabapathy, Niroshana, Crawford, Frances, Kappler, John, Fathman, C. Garrison, Ridgway, William M.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2000
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213496/
https://ncbi.nlm.nih.gov/pubmed/11120769
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