CD1d-mediated Recognition of an α-Galactosylceramide by Natural Killer T Cells Is Highly Conserved through Mammalian Evolution

Natural killer (NK) T cells are a lymphocyte subset with a distinct surface phenotype, an invariant T cell receptor (TCR), and reactivity to CD1. Here we show that mouse NK T cells can recognize human CD1d as well as mouse CD1, and human NK T cells also recognize both CD1 homologues. The unprecedent...

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Huvudupphovsmän: Brossay, Laurent, Chioda, Mariacristina, Burdin, Nicolas, Koezuka, Yasuhiko, Casorati, Giulia, Dellabona, Paolo, Kronenberg, Mitchell
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 1998
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213408/
https://ncbi.nlm.nih.gov/pubmed/9782129
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