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Presentation of peptide antigens by mouse CD1 requires endosomal localization and protein antigen processing

Mouse CD1(mCD1) molecules have been reported to present two types of antigens: peptides or proteins and the glycolipid α-galactosylceramide. Here, we demonstrate that a protein antigen, chicken ovalbumin (Ova), must be processed to generate peptides presented by mCD1 to CD8(+) T cells. The processin...

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Detalhes bibliográficos
Main Authors: Tangri, Shabnam, Brossay, Laurent, Burdin, Nicolas, Lee, Delphine J., Corr, Maripat, Kronenberg, Mitchell
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC24370/
https://ncbi.nlm.nih.gov/pubmed/9826697
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