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Rapid Interferon γ–dependent Clearance of Influenza A Virus and Protection from Consolidating Pneumonitis in Nitric Oxide Synthase 2–deficient Mice

Viral infection often activates the interferon (IFN)-γ–inducible gene, nitric oxide synthase 2 (NOS2). Expression of NOS2 can limit viral growth but may also suppress the immune system and damage tissue. This study assessed each of these effects in genetically deficient NOS2(−/−) mice after infectio...

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Main Authors: Karupiah, Gunasegaran, Chen, Jian-He, Mahalingam, Surendran, Nathan, Carl F., MacMicking, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213404/
https://ncbi.nlm.nih.gov/pubmed/9782132
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