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Independent and Opposing Roles For Btk and Lyn in B and Myeloid Signaling Pathways

Transphosphorylation by Src family kinases is required for the activation of Bruton's tyrosine kinase (Btk). Differences in the phenotypes of Btk(−/−) and lyn(−/−) mice suggest that these kinases may also have independent or opposing functions. B cell development and function were examined in B...

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Autores principales: Satterthwaite, Anne B., Lowell, Clifford A., Khan, Wasif N., Sideras, Paschalis, Alt, Frederick W., Witte, Owen N.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 1998
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213392/
https://ncbi.nlm.nih.gov/pubmed/9730885
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