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Genetic Interaction Between Lyn, Ets1, and Btk in the Control of Antibody Levels(,)
Tight control of B cell differentiation into plasma cells (PCs) is critical for proper immune responses and the prevention of autoimmunity. The Ets1 transcription factor acts in B cells to prevent PC differentiation. Ets1−/− mice accumulate PCs and produce autoantibodies (autoAbs). Ets1 expression i...
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| Publicado no: | J Immunol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4546901/ https://ncbi.nlm.nih.gov/pubmed/26209625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500165 |
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