Blocking TNF-α in mice reduces colorectal carcinogenesis associated with chronic colitis

The inflammatory bowel disease ulcerative colitis (UC) frequently progresses to colon cancer. To understand the mechanisms by which UC patients develop colon carcinomas, we used a mouse model of the disease whereby administration of azoxymethane (AOM) followed by repeated dextran sulfate sodium (DSS...

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Bibliografiset tiedot
Päätekijät: Popivanova, Boryana K., Kitamura, Kazuya, Wu, Yu, Kondo, Toshikazu, Kagaya, Takashi, Kaneko, Shiuchi, Oshima, Masanobu, Fujii, Chifumi, Mukaida, Naofumi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2008
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Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213370/
https://ncbi.nlm.nih.gov/pubmed/18219394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32453
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