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Blocking TNF-α in mice reduces colorectal carcinogenesis associated with chronic colitis
The inflammatory bowel disease ulcerative colitis (UC) frequently progresses to colon cancer. To understand the mechanisms by which UC patients develop colon carcinomas, we used a mouse model of the disease whereby administration of azoxymethane (AOM) followed by repeated dextran sulfate sodium (DSS...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2213370/ https://ncbi.nlm.nih.gov/pubmed/18219394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32453 |
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