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Repression of B7.2 on Self-reactive B Cells Is Essential to Prevent Proliferation and Allow Fas-mediated Deletion by CD4(+) T Cells

Peripheral tolerance mechanisms normally prevent delivery of T cell help to anergic self-reactive B cells that accumulate in the T zones of spleen and lymph nodes. Chronic exposure to self-antigens desensitizes B cell antigen receptor (BCR) signaling on anergic B cells so that they are not stimulate...

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Bibliografski detalji
Glavni autori: Rathmell, Jeffrey C., Fournier, Sylvie, Weintraub, Bennett C., Allison, James P., Goodnow, Christopher C.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 1998
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213352/
https://ncbi.nlm.nih.gov/pubmed/9705947
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