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The immunogenicity of a viral cytotoxic T cell epitope is controlled by its MHC-bound conformation
Thousands of potentially antigenic peptides are encoded by an infecting pathogen; however, only a small proportion induce measurable CD8( + ) T cell responses. To investigate the factors that control peptide immunogenicity, we have examined the cytotoxic T lymphocyte (CTL) response to a previously u...
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| Main Authors: | , , , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Rockefeller University Press
2005
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2213230/ https://ncbi.nlm.nih.gov/pubmed/16275762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050864 |
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