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Lysophosphatidic acid inhibits cholera toxin-induced secretory diarrhea through CFTR-dependent protein interactions

The cystic fibrosis transmembrane conductance regulator (CFTR) is a cAMP-regulated chloride channel localized primarily at the apical or luminal surfaces of epithelial cells that line the airway, gut, and exocrine glands; it is well established that CFTR plays a pivotal role in cholera toxin (CTX)-i...

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Detalhes bibliográficos
Main Authors: Li, Chunying, Dandridge, Keanna S., Di, Anke, Marrs, Kevin L., Harris, Erica L., Roy, Koushik, Jackson, John S., Makarova, Natalia V., Fujiwara, Yuko, Farrar, Patricia L., Nelson, Deborah J., Tigyi, Gabor J., Naren, Anjaparavanda P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213164/
https://ncbi.nlm.nih.gov/pubmed/16203867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050421
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