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Interleukin-7 is necessary to maintain the B cell potential in common lymphoid progenitors

Interleukin-7 (IL-7) promotes survival and expansion of lymphoid precursors. We show here that, in addition, IL-7 has a fundamental role, as early as the stage of the multipotent (B/T/NK) common lymphoid progenitor (CLP), in maintaining the B cell differentiation program open. CLPs generated in the...

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Detalhes bibliográficos
Main Authors: Dias, Sheila, Silva, Hamilton, Cumano, Ana, Vieira, Paulo
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213099/
https://ncbi.nlm.nih.gov/pubmed/15767371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20042393
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