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Anti-CD63 antibodies suppress IgE-dependent allergic reactions in vitro and in vivo

High-affinity IgE receptor (FcɛRI) cross-linking on mast cells (MCs) induces secretion of preformed allergy mediators (degranulation) and synthesis of lipid mediators and cytokines. Degranulation produces many symptoms of immediate-type allergic reactions and is modulated by adhesion to surfaces coa...

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Bibliografski detalji
Glavni autori: Kraft, Stefan, Fleming, Tony, Billingsley, James M., Lin, Shih-Yao, Jouvin, Marie-Hélène, Storz, Peter, Kinet, Jean-Pierre
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2005
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213034/
https://ncbi.nlm.nih.gov/pubmed/15684326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20042085
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