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αvβ3-dependent cross-presentation of matrix metalloproteinase–2 by melanoma cells gives rise to a new tumor antigen

A large array of antigens that are recognized by tumor-specific T cells has been identified and shown to be generated through various processes. We describe a new mechanism underlying T cell recognition of melanoma cells, which involves the generation of a major histocompatibility complex class I–re...

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Autori principali: Godefroy, Emmanuelle, Moreau-Aubry, Agnes, Diez, Elisabeth, Dreno, Brigitte, Jotereau, Francine, Guilloux, Yannick
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212908/
https://ncbi.nlm.nih.gov/pubmed/15998788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20042138
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