NKG2D function protects the host from tumor initiation

The activation NKG2D receptor has been shown to play an important role in the control of experimental tumor growth and metastases expressing ligands for NKG2D; however, a function for this recognition pathway in host protection from de novo tumorigenesis has never been demonstrated. We show that neu...

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Bibliographic Details
Main Authors: Smyth, Mark J., Swann, Jeremy, Cretney, Erika, Zerafa, Nadeen, Yokoyama, Wayne M., Hayakawa, Yoshihiro
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2005
Subjects:
Brief Definitive Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212868/
https://ncbi.nlm.nih.gov/pubmed/16129707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050994
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