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NKG2D Recognition and Perforin Effector Function Mediate Effective Cytokine Immunotherapy of Cancer

Single and combination cytokines offer promise in some patients with advanced cancer. Many spontaneous and experimental cancers naturally express ligands for the lectin-like type-2 transmembrane stimulatory NKG2D immunoreceptor; however, the role this tumor recognition pathway plays in immunotherapy...

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Autori principali: Smyth, Mark J., Swann, Jeremy, Kelly, Janice M., Cretney, Erika, Yokoyama, Wayne M., Diefenbach, Andreas, Sayers, Thomas J., Hayakawa, Yoshihiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211920/
https://ncbi.nlm.nih.gov/pubmed/15545356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041522
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