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IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel

Neuromyelitis optica (NMO) is an inflammatory demyelinating disease that selectively affects optic nerves and spinal cord. It is considered a severe variant of multiple sclerosis (MS), and frequently is misdiagnosed as MS, but prognosis and optimal treatments differ. A serum immunoglobulin G autoant...

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Detalhes bibliográficos
Main Authors: Lennon, Vanda A., Kryzer, Thomas J., Pittock, Sean J., Verkman, A.S., Hinson, Shannon R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212860/
https://ncbi.nlm.nih.gov/pubmed/16087714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050304
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