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Prevention of UV radiation–induced immunosuppression by IL-12 is dependent on DNA repair

The immunostimulatory cytokine IL-12 is able to antagonize immunosuppression induced by solar/ultraviolet (UV) radiation via yet unknown mechanisms. IL-12 was recently found to induce deoxyribonucleic acid (DNA) repair. UV-induced DNA damage is an important molecular trigger for UV-mediated immunosu...

詳細記述

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書誌詳細
主要な著者: Schwarz, Agatha, Maeda, Akira, Kernebeck, Kerstin, van Steeg, Harry, Beissert, Stefan, Schwarz, Thomas
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212783/
https://ncbi.nlm.nih.gov/pubmed/15657287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041212
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