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The role of mitochondria in protection of the heart by preconditioning

A prolonged period of ischaemia followed by reperfusion irreversibly damages the heart. Such reperfusion injury (RI) involves opening of the mitochondrial permeability transition pore (MPTP) under the conditions of calcium overload and oxidative stress that accompany reperfusion. Protection from MPT...

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Detalhes bibliográficos
Main Authors: Halestrap, Andrew P., Clarke, Samantha J., Khaliulin, Igor
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Pub. Co 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212780/
https://ncbi.nlm.nih.gov/pubmed/17631856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2007.05.008
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