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Innate Immune Surveillance of Spontaneous B Cell Lymphomas by Natural Killer Cells and γδ T Cells

Few studies have demonstrated that innate lymphocytes play a major role in preventing spontaneous tumor formation. We evaluated the development of spontaneous tumors in mice lacking β-2 microglobulin (β2m; and thus MHC class I, CD1d, and CD16) and/or perforin, since these tumor cells would be expect...

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Detalhes bibliográficos
Main Authors: Street, Shayna E.A., Hayakawa, Yoshihiro, Zhan, Yifan, Lew, Andrew M., MacGregor, Duncan, Jamieson, Amanda M., Diefenbach, Andreas, Yagita, Hideo, Godfrey, Dale I., Smyth, Mark J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212720/
https://ncbi.nlm.nih.gov/pubmed/15007091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20031981
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