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Perforin-Mediated Cytotoxicity Is Critical for Surveillance of Spontaneous Lymphoma

Immune surveillance by cytotoxic lymphocytes against cancer has been postulated for decades, but direct evidence for the role of cytotoxic lymphocytes in protecting against spontaneous malignancy has been lacking. As the rejection of many experimental cancers by cytotoxic T lymphocytes and natural k...

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Détails bibliographiques
Auteurs principaux: Smyth, Mark J., Thia, Kevin Y.T., Street, Shayna E.A., MacGregor, Duncan, Godfrey, Dale I., Trapani, Joseph A.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2000
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193269/
https://ncbi.nlm.nih.gov/pubmed/10974040
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