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Propagation of Mechanical Stress through the Actin Cytoskeleton toward Focal Adhesions: Model and Experiment

We investigate both theoretically and experimentally how stress is propagated through the actin cytoskeleton of adherent cells and consequentially distributed at sites of focal adhesions (FAs). The actin cytoskeleton is modeled as a two-dimensional cable network with different lattice geometries. Bo...

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Bibliographic Details
Main Authors: Paul, Raja, Heil, Patrick, Spatz, Joachim P., Schwarz, Ulrich S.
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212708/
https://ncbi.nlm.nih.gov/pubmed/17933882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.108688
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