Tumor-infiltrating macrophages and dendritic cells in human colorectal cancer: relation to local regulatory T cells, systemic T-cell response against tumor-associated antigens and survival

INTRODUCTION: Although systemic T-cell responses against tumor antigens and tumor infiltration by T cells have been investigated in colorectal cancer (CRC), the initiation of spontaneous immune responses in situ is not well understood. Macrophages and dendritic cells (DC) play an important role as a...

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Main Authors: Nagorsen, Dirk, Voigt, Sabine, Berg, Erika, Stein, Harald, Thiel, Eckhard, Loddenkemper, Christoph
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2007
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212626/
https://ncbi.nlm.nih.gov/pubmed/18047662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-5-62
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