Comparison of T-cell receptor repertoire restriction in blood and tumor tissue of colorectal cancer patients

Several immunotherapeutic approaches rely on antigen-specific T-cells. Restrictions in the T-cell receptor (TCR) repertoire were reported as indicator of anti-tumor cytotoxic T-lymphocyte (CTL) response in various tumor entities. It is unclear yet whether a TCR restriction in peripheral blood mirror...

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Main Authors: Ochsenreither, Sebastian, Fusi, Alberto, Wojtke, Susanne, Busse, Antonia, Nüssler, Natascha C, Thiel, Eckhard, Keilholz, Ulrich, Nagorsen, Dirk
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873372/
https://ncbi.nlm.nih.gov/pubmed/20385014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-8-35
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