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High Cell Surface Expression of CD4 Allows Distinction of CD4(+)CD25(+) Antigen-specific Effector T Cells from CD4(+)CD25(+) Regulatory T Cells in Murine Experimental Autoimmune Encephalomyelitis

Analysis of T regulatory cells (Treg) and T effector cells (Teff) in experimental autoimmune encephalomyelitis is complicated by the fact that both cell types express CD4 and CD25. We demonstrate that encephalitogenic T cells, following antigen recognition, up regulate cell surface expression of CD4...

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Библиографические подробности
Главные авторы: Li, Jinzhu, Ridgway, William, Fathman, C. Garrison, Tse, Harley Y., Shaw, Michael K.
Формат: Artigo
Язык:Inglês
Опубликовано: 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212588/
https://ncbi.nlm.nih.gov/pubmed/17920698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2007.09.004
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