Potent T Cell Activation with Dimeric Peptide–Major Histocompatibility Complex Class II Ligand: The Role of CD4 Coreceptor

The interaction of the T cell receptor (TCR) with its cognate peptide–major histocompatibility complex (MHC) on the surface of antigen presenting cells (APCs) is a primary event during T cell activation. Here we used a dimeric IE(k)-MCC molecule to study its capacity to activate antigen-specific T c...

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Huvudupphovsmän: Hamad, Abdel Rahim A., O'Herrin, Sean M., Lebowitz, Michael S., Srikrishnan, Ananth, Bieler, Joan, Schneck, Jonathan, Pardoll, Drew
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 1998
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212519/
https://ncbi.nlm.nih.gov/pubmed/9802975
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