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Immature Dendritic Cells Phagocytose Apoptotic Cells via α(v)β(5) and CD36, and Cross-present Antigens to Cytotoxic T Lymphocytes

Dendritic cells, but not macrophages, efficiently phagocytose apoptotic cells and cross-present viral, tumor, and self-antigens to CD8(+) T cells. This in vitro pathway corresponds to the in vivo phenomena of cross-priming and cross-tolerance. Here, we demonstrate that phagocytosis of apoptotic cell...

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Detalhes bibliográficos
Main Authors: Albert, Matthew L., Pearce, S.Frieda A., Francisco, Loise M., Sauter, Birthe, Roy, Pampa, Silverstein, Roy L., Bhardwaj, Nina
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212488/
https://ncbi.nlm.nih.gov/pubmed/9763615
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