Major Histocompatibility Complex Class II Expression by Intrinsic Renal Cells Is Required for Crescentic Glomerulonephritis

The requirement for major histocompatibility complex class II (MHC II) to initiate immune renal injury was studied in a murine model of CD4(+) T cell–dependent crescentic glomerulonephritis (GN). C57BL/6 (MHC II(+/+) ) mice developed crescentic GN with glomerular CD4(+) T cell infiltration and renal...

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Autores principales: Li, Shuo, Kurts, Christian, Köntgen, Frank, Holdsworth, Stephen R., Tipping, Peter G.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 1998
Materias:
Brief Definitive Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212465/
https://ncbi.nlm.nih.gov/pubmed/9687536
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