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The Peripheral Deletion of Autoreactive CD8(+) T Cells Induced by Cross-presentation of Self-antigens Involves Signaling through CD95 (Fas, Apo-1)

Recently, we demonstrated that major histocompatibility complex class I–restricted cross-presentation of exogenous self-antigens can induce peripheral T cell tolerance by deletion of autoreactive CD8(+) T cells. In these studies, naive ovalbumin (OVA)-specific CD8(+) T cells from the transgenic line...

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Detalles Bibliográficos
Main Authors: Kurts, Christian, Heath, William R., Kosaka, Hiroshi, Miller, Jacques F.A.P., Carbone, Francis R.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212451/
https://ncbi.nlm.nih.gov/pubmed/9670055
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