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CD4(+) T Cell Help Impairs CD8(+) T Cell Deletion Induced by Cross-presentation of Self-Antigens and Favors Autoimmunity
Self-antigens expressed in extrathymic tissues such as the pancreas can be transported to draining lymph nodes and presented in a class I–restricted manner by bone marrow-derived antigen-presenting cells. Such cross-presentation of self-antigens leads to CD8(+) T cell tolerance induction via deletio...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2199175/ https://ncbi.nlm.nih.gov/pubmed/9396776 |
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