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Major Histocompatibility Complex Class I–restricted Cross-presentation Is Biased towards High Dose Antigens and Those Released during Cellular Destruction

Naive T cells recirculate mainly within the secondary lymphoid compartment, but once activated they can enter peripheral tissues and perform effector functions. To activate naive T cells, foreign antigens must traffic from the site of infection to the draining lymph nodes, where they can be presente...

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Detalhes bibliográficos
Main Authors: Kurts, Christian, Miller, Jacques F.A.P., Subramaniam, Rathan M., Carbone, Francis R., Heath, William R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212442/
https://ncbi.nlm.nih.gov/pubmed/9670054
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